eRF3/GSPT1 anticorps
Aperçu rapide pour eRF3/GSPT1 anticorps (ABIN7073859)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Rat
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse eRF3/GSPT1
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Indications d'application
- WB (H,M,R) 1:500-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- eRF3/GSPT1
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Sujet
- ERF3a is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94 % sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth.
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Poids moléculaire
- 72 kDa
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ID gène
- 14852
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NCBI Accession
- NP_001123480
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UniProt
- Q8R050
Antigène
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